Analysis of hypermethylation and expression profiles of APC and ATM genes in patients with oral squamous cell carcinoma

BACKGROUND: Adenomatous polyposis coli (APC) and Ataxia-telangiectasia-mutated (ATM) gene products have an important role in cell cycle control and maintenance of genomic stability. Our aim was to analyze ATM and APC methylation and its relationship with oral squamous cell carcinoma (OSCC). MATERIAL...

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Main Authors: Rigi-Ladiz, Mohammad Ayub, Kordi-Tamandani, Dor Mohammad, Torkamanzehi, Adam
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303468/
https://ncbi.nlm.nih.gov/pubmed/22414247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-3-6
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