Hyaluronan synthase 3 mediated oncogenic action through forming inter-regulation loop with tumor necrosis factor alpha in oral cancer

Hyaluronan (HA) is a major extracellular matrix component. However, its role and mediation in oral cancer remains elusive. Hyaluronan synthase 3 (HAS3), involved in pro-inflammatory short chain HA synthesis, was the predominant synthase in oral cancer cells and tissues. HAS3 overexpression significa...

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Опубликовано в: :Oncotarget
Главные авторы: Kuo, Yi-Zih, Fang, Wei-Yu, Huang, Cheng-Chih, Tsai, Sen-Tien, Wang, Yi-Ching, Yang, Chih-Li, Wu, Li-Wha
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2017
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362506/
https://ncbi.nlm.nih.gov/pubmed/28107185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14697
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