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The Tumor Suppressor TGFBR3 Blocks Lymph Node Metastasis in Head and Neck Cancer

The TGF-β type III receptor (TGFBR3) is an essential constituent of the TGF-β signaling. In this study, we observed a down-regulation of TGFBR3 in oral cancer, a subtype of head and neck cancer (HNC), and patients with low TGFBR3 had poor clinical outcomes. Ectopic expression of TGFBR3 decreased mig...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Fang, Wei-Yu, Kuo, Yi-Zih, Chang, Jang-Yang, Hsiao, Jenn-Ren, Kao, Hung-Ying, Tsai, Sen-Tien, Wu, Li-Wha
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352722/
https://ncbi.nlm.nih.gov/pubmed/32471132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061375
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