Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation

Hyperhomocysteinemia (HHcy) can result from liver disease or dysfunction and further alters intracellular lipid metabolism. Cytochrome P450 (CYP) arachidonic acid epoxygenases are expressed in human cancers and promote cancer metastasis. This study explored the interaction of Hcy and CYP450 metaboli...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Donghong, Lou, Jinli, Zhang, Xu, Zhang, Lin, Wang, Fei, Xu, Danfei, Niu, Na, Wang, Yidong, Wu, Yue, Cui, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362492/
https://ncbi.nlm.nih.gov/pubmed/28030819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14165
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