Inflammatory cytokines IL-17 and TNF-α up-regulate PD-L1 expression in human prostate and colon cancer cells

Programmed cell death protein 1 (PD-1) acts on PD-1 ligands (PD-L1 and PD-L2) to suppress activation of cytotoxic T lymphocytes. Interleukin-17 (IL-17) and tumor necrosis factor-α (TNF-α) are co-expressed by T helper 17 (T(H)17) cells in many tumors. The purpose of this study was to test if IL-17 an...

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Detalhes bibliográficos
Publicado no:Immunol Lett
Main Authors: Wang, Xun, Yang, Lingyun, Huang, Feng, Zhang, Qiuyang, Liu, Sen, Ma, Lin, You, Zongbing
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362328/
https://ncbi.nlm.nih.gov/pubmed/28223102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2017.02.006
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