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Inflammatory cytokines IL-17 and TNF-α up-regulate PD-L1 expression in human prostate and colon cancer cells
Programmed cell death protein 1 (PD-1) acts on PD-1 ligands (PD-L1 and PD-L2) to suppress activation of cytotoxic T lymphocytes. Interleukin-17 (IL-17) and tumor necrosis factor-α (TNF-α) are co-expressed by T helper 17 (T(H)17) cells in many tumors. The purpose of this study was to test if IL-17 an...
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| Veröffentlicht in: | Immunol Lett |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5362328/ https://ncbi.nlm.nih.gov/pubmed/28223102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2017.02.006 |
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