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In vitro reconstitution demonstrates the cell wall ligase activity of LCP proteins

Sacculus is a peptidoglycan matrix that protects bacteria from osmotic lysis. In Gram-positive organisms, the sacculus is densely functionalized with glycopolymers important for survival, but how assembly occurs is not known. In Staphylococcus aureus, three LCP family members have been implicated in...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Schaefer, Kaitlin, Matano, Leigh M., Qiao, Yuan, Kahne, Daniel, Walker, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362317/
https://ncbi.nlm.nih.gov/pubmed/28166208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2302
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