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Expression, regulation, and function of drug transporters in cervicovaginal tissues of a mouse model used for microbicide testing
P-glycoprotein (P-gp), breast cancer resistance protein (BCRP), and multidrug resistance protein 4 (MRP4) are three efflux transporters that play key roles in the pharmacokinetics of antiretroviral drugs used in the pre-exposure prophylaxis of HIV sexual transmission. In this study, we investigated...
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| Publicado en: | Biochem Pharmacol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5362249/ https://ncbi.nlm.nih.gov/pubmed/27453435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.07.009 |
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