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Expression, regulation, and function of drug transporters in cervicovaginal tissues of a mouse model used for microbicide testing

P-glycoprotein (P-gp), breast cancer resistance protein (BCRP), and multidrug resistance protein 4 (MRP4) are three efflux transporters that play key roles in the pharmacokinetics of antiretroviral drugs used in the pre-exposure prophylaxis of HIV sexual transmission. In this study, we investigated...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Zhou, Tian, Hu, Minlu, Pearlman, Andrew, Rohan, Lisa C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362249/
https://ncbi.nlm.nih.gov/pubmed/27453435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.07.009
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