Treatment monitoring in metastatic colorectal cancer patients by quantification and KRAS genotyping of circulating cell-free DNA

Treatment of metastatic colorectal cancer (CRC) has continuously improved over the last decade. However, disease monitoring remains underdeveloped and mostly dependent on imaging e.g. RECIST 1.1 criteria. The genetic landscape of individual cancers and subsequently occurring treatment-induced evolut...

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Udgivet i:PLoS One
Main Authors: Berger, Andreas W., Schwerdel, Daniel, Welz, Hanna, Marienfeld, Ralf, Schmidt, Stefan A., Kleger, Alexander, Ettrich, Thomas J., Seufferlein, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362218/
https://ncbi.nlm.nih.gov/pubmed/28328955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174308
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