Monitoring circulating tumor DNA revealed dynamic changes in KRAS status in patients with metastatic colorectal cancer

KRAS mutated circulating tumor DNA (MctDNA) can be monitored in the blood of patients with metastatic colorectal cancer (mCRC), but dynamic changes have not been determined. Four hundred and fifty-seven plasma samples were collected prospectively from 85 mCRC patients who underwent chemotherapy. Mct...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Takayama, Yuji, Suzuki, Koichi, Muto, Yuta, Ichida, Kosuke, Fukui, Taro, Kakizawa, Nao, Ishikawa, Hideki, Watanabe, Fumiaki, Hasegawa, Fumi, Saito, Masaaki, Tsujinaka, Shingo, Futsuhara, Kazushige, Miyakura, Yasuyuki, Noda, Hiroshi, Konishi, Fumio, Rikiyama, Toshiki
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2018
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966256/
https://ncbi.nlm.nih.gov/pubmed/29849949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25309
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