Monitoring circulating tumor DNA revealed dynamic changes in KRAS status in patients with metastatic colorectal cancer

KRAS mutated circulating tumor DNA (MctDNA) can be monitored in the blood of patients with metastatic colorectal cancer (mCRC), but dynamic changes have not been determined. Four hundred and fifty-seven plasma samples were collected prospectively from 85 mCRC patients who underwent chemotherapy. Mct...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Takayama, Yuji, Suzuki, Koichi, Muto, Yuta, Ichida, Kosuke, Fukui, Taro, Kakizawa, Nao, Ishikawa, Hideki, Watanabe, Fumiaki, Hasegawa, Fumi, Saito, Masaaki, Tsujinaka, Shingo, Futsuhara, Kazushige, Miyakura, Yasuyuki, Noda, Hiroshi, Konishi, Fumio, Rikiyama, Toshiki
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966256/
https://ncbi.nlm.nih.gov/pubmed/29849949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25309
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