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Activation of Ventral Tegmental Area 5-HT(2C) Receptors Reduces Incentive Motivation

Obesity is primarily due to food intake in excess of the body's energetic requirements, intake that is not only associated with hunger but also the incentive value of food. The 5-hydroxytryptamine 2C receptor (5-HT(2C)R) is a target for the treatment of human obesity. Mechanistically, 5-HT(2C)R...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Valencia-Torres, Lourdes, Olarte-Sánchez, Cristian M, Lyons, David J, Georgescu, Teodora, Greenwald-Yarnell, Megan, Myers, Martin G, Bradshaw, Christopher M, Heisler, Lora K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362069/
https://ncbi.nlm.nih.gov/pubmed/27882999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.264
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