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Reducing Ventral Tegmental Dopamine D2 Receptor Expression Selectively Boosts Incentive Motivation

Altered mesolimbic dopamine signaling has been widely implicated in addictive behavior. For the most part, this work has focused on dopamine within the striatum, but there is emerging evidence for a role of the auto-inhibitory, somatodendritic dopamine D2 receptor (D2R) in the ventral tegmental area...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: de Jong, Johannes W, Roelofs, Theresia J M, Mol, Frédérique M U, Hillen, Anne E J, Meijboom, Katharina E, Luijendijk, Mieneke C M, van der Eerden, Harrie A M, Garner, Keith M, Vanderschuren, Louk J M J, Adan, Roger A H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613606/
https://ncbi.nlm.nih.gov/pubmed/25735756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.60
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