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Analysis of Anti-Influenza Virus Neuraminidase Antibodies in Children, Adults, and the Elderly by ELISA and Enzyme Inhibition: Evidence for Original Antigenic Sin

Antibody responses to influenza virus hemagglutinin provide protection against infection and are well studied. Less is known about the human antibody responses to the second surface glycoprotein, neuraminidase. Here, we assessed human antibody reactivity to a panel of N1, N2, and influenza B virus n...

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Bibliographische Detailangaben
Veröffentlicht in:mBio
Hauptverfasser: Rajendran, Madhusudan, Nachbagauer, Raffael, Ermler, Megan E., Bunduc, Paul, Amanat, Fatima, Izikson, Ruvim, Cox, Manon, Palese, Peter, Eichelberger, Maryna, Krammer, Florian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362038/
https://ncbi.nlm.nih.gov/pubmed/28325769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02281-16
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