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Global identification and analysis of isozyme-specific possible substrates crosslinked by transglutaminases using substrate peptides in mouse liver fibrosis

The transglutaminase (TG) family comprises eight isozymes that form the isopeptide bonds between glutamine and lysine residues and contribute to the fibrotic diseases via crosslinking-mediated stabilization of ECM and the activation of TGF-β in several tissues. However, despite a growing body of evi...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Tatsukawa, Hideki, Tani, Yuji, Otsu, Risa, Nakagawa, Haruka, Hitomi, Kiyotaka
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361200/
https://ncbi.nlm.nih.gov/pubmed/28327670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45049
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