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Global identification and analysis of isozyme-specific possible substrates crosslinked by transglutaminases using substrate peptides in mouse liver fibrosis

The transglutaminase (TG) family comprises eight isozymes that form the isopeptide bonds between glutamine and lysine residues and contribute to the fibrotic diseases via crosslinking-mediated stabilization of ECM and the activation of TGF-β in several tissues. However, despite a growing body of evi...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Tatsukawa, Hideki, Tani, Yuji, Otsu, Risa, Nakagawa, Haruka, Hitomi, Kiyotaka
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361200/
https://ncbi.nlm.nih.gov/pubmed/28327670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45049
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