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Global identification and analysis of isozyme-specific possible substrates crosslinked by transglutaminases using substrate peptides in mouse liver fibrosis

The transglutaminase (TG) family comprises eight isozymes that form the isopeptide bonds between glutamine and lysine residues and contribute to the fibrotic diseases via crosslinking-mediated stabilization of ECM and the activation of TGF-β in several tissues. However, despite a growing body of evi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tatsukawa, Hideki, Tani, Yuji, Otsu, Risa, Nakagawa, Haruka, Hitomi, Kiyotaka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361200/
https://ncbi.nlm.nih.gov/pubmed/28327670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45049
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