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Aspirin induces cell death by directly modulating mitochondrial voltage-dependent anion channel (VDAC)
Aspirin induces apoptotic cell death in various cancer cell lines. Here we showed that silencing of VDAC1 protected HeLa cells from aspirin-induced cell death. Compared to the wild type cells, VDAC1 knocked down cells showed lesser change of mitochondrial membrane potential (Δψ(m)), upon aspirin tre...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5361111/ https://ncbi.nlm.nih.gov/pubmed/28327594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45184 |
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