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An easy method for preparation of Cre-loxP regulated fluorescent adenoviral expression vectors and its application for direct reprogramming into hepatocytes

The recombinant adenoviral gene expression system is a powerful tool for gene delivery. However, it is difficult to obtain high titers of infectious virus, principally due to the toxicity of the expressed gene which affects on virus replication in the host HEK293 cells. To avoid these problems, we g...

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Bibliografische gegevens
Gepubliceerd in:Biotechnol Rep (Amst)
Hoofdauteurs: Kurihara, Chitose, Nakade, Koji, Pan, Jianzhi, Huang, Jing, Wasylyk, Bohdan, Obata, Yuichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361070/
https://ncbi.nlm.nih.gov/pubmed/28352551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2016.10.003
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