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An easy method for preparation of Cre-loxP regulated fluorescent adenoviral expression vectors and its application for direct reprogramming into hepatocytes

The recombinant adenoviral gene expression system is a powerful tool for gene delivery. However, it is difficult to obtain high titers of infectious virus, principally due to the toxicity of the expressed gene which affects on virus replication in the host HEK293 cells. To avoid these problems, we g...

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Bibliografski detalji
Izdano u:Biotechnol Rep (Amst)
Glavni autori: Kurihara, Chitose, Nakade, Koji, Pan, Jianzhi, Huang, Jing, Wasylyk, Bohdan, Obata, Yuichi
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361070/
https://ncbi.nlm.nih.gov/pubmed/28352551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2016.10.003
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