Stimulation of cardiomyocyte regeneration in neonatal mice and in human myocardium with neuregulin reveals a therapeutic window

BACKGROUND: Pediatric patients with heart failure are treated with medical therapies that were developed for adult patients. These therapies have been shown to be ineffective in pediatric trials, leading to the recognition that new pediatric-specific therapies must be developed. We have previously s...

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Bibliografske podrobnosti
izdano v:Sci Transl Med
Main Authors: Polizzotti, Brian D., Ganapathy, Balakrishnan, Walsh, Stuart, Choudhury, Sangita, Ammanamanchi, Niyatie, Bennett, David G., dos Remedios, Cristobal G., Haubner, Bernhard J., Penninger, Josef M., Kuhn, Bernhard
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360874/
https://ncbi.nlm.nih.gov/pubmed/25834111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa5171
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