Stimulation of cardiomyocyte regeneration in neonatal mice and in human myocardium with neuregulin reveals a therapeutic window

BACKGROUND: Pediatric patients with heart failure are treated with medical therapies that were developed for adult patients. These therapies have been shown to be ineffective in pediatric trials, leading to the recognition that new pediatric-specific therapies must be developed. We have previously s...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Polizzotti, Brian D., Ganapathy, Balakrishnan, Walsh, Stuart, Choudhury, Sangita, Ammanamanchi, Niyatie, Bennett, David G., dos Remedios, Cristobal G., Haubner, Bernhard J., Penninger, Josef M., Kuhn, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360874/
https://ncbi.nlm.nih.gov/pubmed/25834111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa5171
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