Efficacy and Blood Plasmalogen Changes by Oral Administration of Plasmalogen in Patients with Mild Alzheimer's Disease and Mild Cognitive Impairment: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial

BACKGROUND: Plasmalogens (Pls) reportedly decreased in postmortem brain and in the blood of patients with Alzheimer's disease (AD). Recently we showed that intraperitoneal administration of Pls improved cognitive function in experimental animals. In the present trial, we tested the efficacy of...

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Detaylı Bibliyografya
Yayımlandı:EBioMedicine
Asıl Yazarlar: Fujino, Takehiko, Yamada, Tatsuo, Asada, Takashi, Tsuboi, Yoshio, Wakana, Chikako, Mawatari, Shiro, Kono, Suminori
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360580/
https://ncbi.nlm.nih.gov/pubmed/28259590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.02.012
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