Efficacy and Blood Plasmalogen Changes by Oral Administration of Plasmalogen in Patients with Mild Alzheimer's Disease and Mild Cognitive Impairment: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial

BACKGROUND: Plasmalogens (Pls) reportedly decreased in postmortem brain and in the blood of patients with Alzheimer's disease (AD). Recently we showed that intraperitoneal administration of Pls improved cognitive function in experimental animals. In the present trial, we tested the efficacy of...

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Vydáno v:EBioMedicine
Hlavní autoři: Fujino, Takehiko, Yamada, Tatsuo, Asada, Takashi, Tsuboi, Yoshio, Wakana, Chikako, Mawatari, Shiro, Kono, Suminori
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360580/
https://ncbi.nlm.nih.gov/pubmed/28259590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.02.012
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