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Virus-specific CD8(+) T cells infiltrate melanoma lesions and retain function independent of PD-1 expression

It is well known that CD8(+) tumor infiltrating lymphocytes (TIL) are correlated with positive prognoses in cancer patients and used to determine efficacy of immune therapies. While it is generally assumed that CD8(+) TIL will be tumor associated antigen (TAA)-specific, it is unknown whether CD8(+)...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Erkes, Dan A., Smith, Corinne J., Wilski, Nicole A., Caldeira-Dantas, Sofia, Mohgbeli, Toktam, Snyder, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360480/
https://ncbi.nlm.nih.gov/pubmed/28202614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601064
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