Reversal learning deficits associated with increased frontal cortical BDNF-TrkB signaling in a prenatal cocaine exposure mouse model

Prenatal cocaine exposure remains a major public health concern because of its adverse impact on cognitive function in children and adults. We report that prenatal cocaine exposure produces significant deficits in reversal learning, a key component of cognitive flexibility, in a mouse model. We used...

Full description

Saved in:
Bibliographic Details
Published in:Dev Neurosci
Main Authors: McCarthy, Deirdre M., Bell, Genevieve A., Cannon, Elisa N., Mueller, Kaly A., Huizenga, Megan N., Sadri-Vakili, Ghazaleh, Fadool, Debra A., Bhide, Pradeep G.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360472/
https://ncbi.nlm.nih.gov/pubmed/27951531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000452739
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items