Reversal learning deficits associated with increased frontal cortical BDNF-TrkB signaling in a prenatal cocaine exposure mouse model

Prenatal cocaine exposure remains a major public health concern because of its adverse impact on cognitive function in children and adults. We report that prenatal cocaine exposure produces significant deficits in reversal learning, a key component of cognitive flexibility, in a mouse model. We used...

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Veröffentlicht in:Dev Neurosci
Hauptverfasser: McCarthy, Deirdre M., Bell, Genevieve A., Cannon, Elisa N., Mueller, Kaly A., Huizenga, Megan N., Sadri-Vakili, Ghazaleh, Fadool, Debra A., Bhide, Pradeep G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360472/
https://ncbi.nlm.nih.gov/pubmed/27951531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000452739
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