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Regulation of Glucose Uptake and Enteroendocrine Function by the Intestinal Epithelial Insulin Receptor

Insulin receptors (IRs) and IGF-I receptors (IGF-IR) are major regulators of metabolism and cell growth throughout the body; however, their roles in the intestine remain controversial. Here we show that genetic ablation of the IR or IGF-IR in intestinal epithelial cells of mice does not impair intes...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Ussar, Siegfried, Haering, Max-Felix, Fujisaka, Shiho, Lutter, Dominik, Lee, Kevin Y., Li, Ning, Gerber, Georg K., Bry, Lynn, Kahn, C. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360299/
https://ncbi.nlm.nih.gov/pubmed/28096258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1349
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