HCV coinfection contributes to HIV pathogenesis by increasing immune exhaustion in CD8 T-cells

BACKGROUND: There are several contributors to HIV-pathogenesis or insufficient control of the infection. However, whether HIV/HCV-coinfected population exhibits worst evolution of HIV-pathogenesis remains unclear. Recently, some markers of immune exhaustion have been proposed as preferentially upreg...

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Udgivet i:PLoS One
Main Authors: Rallón, Norma, García, Marcial, García-Samaniego, Javier, Rodríguez, Noelia, Cabello, Alfonso, Restrepo, Clara, Álvarez, Beatriz, García, Rosa, Górgolas, Miguel, Benito, José M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360268/
https://ncbi.nlm.nih.gov/pubmed/28323897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173943
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