Lawsonia intracellularis exploits β-catenin/Wnt and Notch signalling pathways during infection of intestinal crypt to alter cell homeostasis and promote cell proliferation

Lawsonia intracellularis is an obligate intracellular bacterial pathogen that causes proliferative enteropathy (PE) in pigs. L. intracellularis infection causes extensive intestinal crypt cell proliferation and inhibits secretory and absorptive cell differentiation. However, the affected host upstre...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Huan, Yang W., Bengtsson, Rebecca J., MacIntyre, Neil, Guthrie, Jack, Finlayson, Heather, Smith, Sionagh H., Archibald, Alan L., Ait-Ali, Tahar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360247/
https://ncbi.nlm.nih.gov/pubmed/28323899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173782
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