Lawsonia intracellularis exploits β-catenin/Wnt and Notch signalling pathways during infection of intestinal crypt to alter cell homeostasis and promote cell proliferation

Lawsonia intracellularis is an obligate intracellular bacterial pathogen that causes proliferative enteropathy (PE) in pigs. L. intracellularis infection causes extensive intestinal crypt cell proliferation and inhibits secretory and absorptive cell differentiation. However, the affected host upstre...

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Publicat a:PLoS One
Autors principals: Huan, Yang W., Bengtsson, Rebecca J., MacIntyre, Neil, Guthrie, Jack, Finlayson, Heather, Smith, Sionagh H., Archibald, Alan L., Ait-Ali, Tahar
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360247/
https://ncbi.nlm.nih.gov/pubmed/28323899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173782
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