Lawsonia intracellularis exploits β-catenin/Wnt and Notch signalling pathways during infection of intestinal crypt to alter cell homeostasis and promote cell proliferation

Lawsonia intracellularis is an obligate intracellular bacterial pathogen that causes proliferative enteropathy (PE) in pigs. L. intracellularis infection causes extensive intestinal crypt cell proliferation and inhibits secretory and absorptive cell differentiation. However, the affected host upstre...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Huan, Yang W., Bengtsson, Rebecca J., MacIntyre, Neil, Guthrie, Jack, Finlayson, Heather, Smith, Sionagh H., Archibald, Alan L., Ait-Ali, Tahar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360247/
https://ncbi.nlm.nih.gov/pubmed/28323899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173782
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