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The structure of carbonmonoxy neuroglobin reveals a heme-sliding mechanism for control of ligand affinity
Neuroglobin (Ngb), a globular heme protein expressed in the brain of vertebrates, binds oxygen reversibly, with an affinity comparable to myoglobin (Mb). Despite low sequence identity, the overall 3D fold of Ngb and Mb is very similar. Unlike in Mb, in Ngb the sixth coordination position of the heme...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC536024/ https://ncbi.nlm.nih.gov/pubmed/15548613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407633101 |
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