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Molecular basis of Kir6.2 mutations associated with neonatal diabetes or neonatal diabetes plus neurological features

Inwardly rectifying potassium channels (Kir channels) control cell membrane K(+) fluxes and electrical signaling in diverse cell types. Heterozygous mutations in the human Kir6.2 gene (KCNJ11), the pore-forming subunit of the ATP-sensitive (K(ATP)) channel, cause permanent neonatal diabetes mellitus...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Proks, Peter, Antcliff, Jennifer F., Lippiat, Jon, Gloyn, Anna L., Hattersley, Andrew T., Ashcroft, Frances M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC536014/
https://ncbi.nlm.nih.gov/pubmed/15583126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404756101
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