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Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment
Chimeric antigen receptor (CAR) T-cell therapy represents a revolutionary treatment for haematological malignancies (i.e. B-ALL). However, the success of this type of treatment has not yet been achieved in solid tumors. One hypothesis is that the immunosuppressive nature of the tumor microenvironmen...
Gardado en:
| Publicado en: | J Immunother Cancer |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5359946/ https://ncbi.nlm.nih.gov/pubmed/28331617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-017-0230-9 |
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