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Binding of smoothelin-like 1 to tropomyosin and calmodulin is mutually exclusive and regulated by phosphorylation

BACKGROUND: The smoothelin-like 1 protein (SMTNL1) can associate with tropomyosin (Tpm) and calmodulin (CaM), two proteins essential to the smooth muscle contractile process. SMTNL1 is phosphorylated at Ser301 by protein kinase A during calcium desensitization in smooth muscle, yet the effect of SMT...

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Bibliografske podrobnosti
izdano v:BMC Biochem
Main Authors: Ulke-Lemée, Annegret, Sun, David Hao, Ishida, Hiroaki, Vogel, Hans J., MacDonald, Justin A.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359911/
https://ncbi.nlm.nih.gov/pubmed/28320308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12858-017-0080-6
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