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Constant domains influence binding of mouse–human chimeric antibodies to the capsular polypeptide of Bacillus anthracis

Our laboratory previously described the binding characteristics of the murine IgG3 monoclonal antibody (MuAb) F26G3. This antibody binds the poly-glutamic acid capsule (PGA) of Bacillus anthracis, an essential virulence factor in the progression of anthrax. F26G3 IgG3 MuAb binds PGA with a relativel...

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Bibliografiset tiedot
Julkaisussa:Virulence
Päätekijät: Hubbard, Mark A, Thorkildson, Peter, Kozel, Thomas R, AuCoin, David P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359726/
https://ncbi.nlm.nih.gov/pubmed/23863605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/viru.25711
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