The protective effects of shikonin on hepatic ischemia/reperfusion injury are mediated by the activation of the PI3K/Akt pathway

Hepatic ischemia/reperfusion (I/R) injury, which can result in severe liver injury and dysfunction, occurs in a variety of conditions such as liver transplantation, shock, and trauma. Cell death in hepatic I/R injury has been linked to apoptosis and autophagy. Shikonin plays a significant protective...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Liu, Tong, Zhang, QingHui, Mo, Wenhui, Yu, Qiang, Xu, Shizan, Li, Jingjing, Li, Sainan, Feng, Jiao, Wu, Liwei, Lu, Xiya, Zhang, Rong, Li, Linqiang, Cheng, Keran, Zhou, Yuqing, Zhou, Shunfeng, Kong, Rui, Wang, Fan, Dai, Weiqi, Chen, Kan, Xia, Yujing, Lu, Jie, Zhou, Yingqun, Zhao, Yan, Guo, Chuanyong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359611/
https://ncbi.nlm.nih.gov/pubmed/28322249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44785
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