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Functional confirmation of PLAG1 as the candidate causative gene underlying major pleiotropic effects on body weight and milk characteristics

A major pleiotropic quantitative trait locus (QTL) located at ~25 Mbp on bovine chromosome 14 affects a myriad of growth and developmental traits in Bos taurus and indicus breeds. These QTL have been attributed to two functional variants in the bidirectional promoter of PLAG1 and CHCHD7. Although PL...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Fink, Tania, Tiplady, Kathryn, Lopdell, Thomas, Johnson, Thomas, Snell, Russell G., Spelman, Richard J., Davis, Stephen R., Littlejohn, Mathew D.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359603/
https://ncbi.nlm.nih.gov/pubmed/28322319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44793
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