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A new electro-optical approach for conductance measurement: an assay for the study of drugs acting on ligand-gated ion channels
Ligand gated ion channels are involved in many pathophysiological processes and represent a relevant, although challenging, target for drug discovery. We propose an innovative electro-optical approach to their analysis able to derive membrane conductance values from the local membrane potential chan...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5359596/ https://ncbi.nlm.nih.gov/pubmed/28322303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44843 |
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