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Therapy targeted to the metastatic niche is effective in a model of stage IV breast cancer
Treatment of stage IV metastatic breast cancer patients is limited to palliative options and represents an unmet clinical need. Here, we demonstrate that pharmacological inhibition of miRNA-10b - a master regulator of metastatic cell viability – leads to elimination of distant metastases in a mouse...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5359550/ https://ncbi.nlm.nih.gov/pubmed/28322342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45060 |
| Oznake: |
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