A Two-Tiered Mechanism Enables Localized Cdc42 Signaling during Enterocyte Polarization

Signaling by the small GTPase Cdc42 governs a diverse set of cellular processes that contribute to tissue morphogenesis. Since these processes often require highly localized signaling, Cdc42 activity must be clustered in order to prevent ectopic signaling. During cell polarization, apical Cdc42 sign...

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Опубликовано в: :Mol Cell Biol
Главные авторы: Bruurs, Lucas J. M., Zwakenberg, Susan, van der Net, Mirjam C., Zwartkruis, Fried J., Bos, Johannes L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359428/
https://ncbi.nlm.nih.gov/pubmed/28069739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00547-16
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