Streptomyces venezuelae ISP5230 Maintains Excretion of Jadomycin upon Disruption of the MFS Transporter JadL Located within the Natural Product Biosynthetic Gene Cluster

JadL was identified as a Major Facilitator Superfamily (MFS) transporter (T.C. 2.A.1) through sequence homology. The protein is encoded by jadL, situated within the jadomycin biosynthetic gene cluster. JadL has, therefore, been assigned a putative role in host defense by exporting its probable subst...

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Vydáno v:Front Microbiol
Hlavní autoři: Forget, Stephanie M., McVey, Jennifer, Vining, Leo C., Jakeman, David L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359229/
https://ncbi.nlm.nih.gov/pubmed/28377749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00432
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