Biomarker-driven phenotyping in Parkinson disease: a translational missing link in disease-modifying clinical trials

Past clinical trials of putative neuroprotective therapies have targeted Parkinson disease (PD) as a single pathogenic disease entity. From an Oslerian clinico-pathologic perspective, the wide complexity of PD converges into Lewy bodies and justifies a reductionist approach to PD: a single-mechanism...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mov Disord
Main Authors: Espay, Alberto J., Schwarzschild, Michael A., Tanner, Caroline M., Fernandez, Hubert H, Simon, David K., Leverenz, James B., Merola, Aristide, Chen-Plotkin, Alice, Brundin, Patrik, Kauffman, Marcelo A., Erro, Roberto, Kieburtz, Karl, Woo, Daniel, Macklin, Eric A., Standaert, David G., Lang, Anthony E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359057/
https://ncbi.nlm.nih.gov/pubmed/28233927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.26913
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados