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MENA confers resistance to paclitaxel in triple-negative breast cancer

Taxane therapy remains the standard of care for triple-negative breast cancer. However, high frequencies of recurrence and progression in treated patients indicate that metastatic breast cancer cells can acquire resistance to this drug. The actin regulatory protein MENA, particularly its invasive is...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Oudin, Madeleine J., Barbier, Lucie, Schäfer, Claudia, Kosciuk, Tatsiana, Miller, Miles A., Han, Sangyoon, Jonas, Oliver, Lauffenburger, Douglas A., Gertler, Frank B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359014/
https://ncbi.nlm.nih.gov/pubmed/27811011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0413
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