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Mutation of the N-Terminal Region of Chikungunya Virus Capsid Protein: Implications for Vaccine Design

Mosquito-transmitted chikungunya virus (CHIKV) is an arthritogenic alphavirus of the Togaviridae family responsible for frequent outbreaks of arthritic disease in humans. Capsid protein, a structural protein encoded by the CHIKV RNA genome, is able to translocate to the host cell nucleolus. In encep...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Taylor, Adam, Liu, Xiang, Zaid, Ali, Goh, Lucas Y. H., Hobson-Peters, Jody, Hall, Roy A., Merits, Andres, Mahalingam, Suresh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358915/
https://ncbi.nlm.nih.gov/pubmed/28223458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01970-16
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