Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression

A critical role of circadian oscillators in orchestrating insulin secretion and islet gene transcription has been demonstrated recently. However, these studies focused on whole islets and did not explore the interplay between α-cell and β-cell clocks. We performed a parallel analysis of the molecula...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Petrenko, Volodymyr, Saini, Camille, Giovannoni, Laurianne, Gobet, Cedric, Sage, Daniel, Unser, Michael, Heddad Masson, Mounia, Gu, Guoqiang, Bosco, Domenico, Gachon, Frédéric, Philippe, Jacques, Dibner, Charna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358758/
https://ncbi.nlm.nih.gov/pubmed/28275001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.290379.116
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge