PP28. THERAPEUTIC COMPOUND DISCOVERY AND VALIDATION OF DRUGS TARGETING A RECURRENT GLIOBLASTOMA (GBM) PHENOTYPE USING LINCS COMPOUNDS VIA QUADRATIC ANALYSES

Glioblastoma (GBM) is the most prevalent and aggressive of malignant primary brain tumours. Despite multi-modal therapy, including surgical resection, radiotherapy and chemotherapy, GBM continues to be uniformly lethal, with a median survival of 12–18 months from the time of diagnosis. The resistanc...

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Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Rashid, Dr Shahnaz Al, O’Reilly, Dr Paul, dunne, Dr philip, Alderdice, Mr Matthew, Flannery, Dr Thomas, Prise, Prof Kevin, Zhang, Dr Shu-Dong, McArt, Dr Darragh
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
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Abstracts
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358602/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now293.027
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