PP17. RHO GTPASE SIGNALLING IN CANCER CELL INVASION AND ANGIOGENESIS IN BRAIN TUMOURS

INTRODUCTION: Rho GTPases are molecular switches that cycle between GDP-bound inactive and GTP-bound active states. They transduce signals from the extracellular environment and downstream of oncogenes to control the actin cytoskeleton, and cellular functions including cell motility, cell cycle prog...

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Published in:Neuro Oncol
Main Authors: Egnuni, Mr Teklu, Grant, Michael, Bruning-Richardson, Dr Anke, Speirs, Prof Valerie, Chakrabarty, Dr Aruna, Wurdak, Dr Heiko, Lorger, Dr Mihaela, Short, Prof Susan, Mavria, Dr Georgia
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358595/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now293.016
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