TAM receptors regulate multiple features of microglial physiology

Microglia are damage sensors for the central nervous system (CNS), and the phagocytes responsible for the routine non-inflammatory clearance of dead brain cells(1). Here we show that the TAM receptor tyrosine kinases Mer and Axl(2) regulate these microglial functions. We find that mice deficient in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Fourgeaud, Lawrence, Través, Paqui G., Tufail, Yusuf, Leal-Bailey, Humberto, Lew, Erin D., Burrola, Patrick G., Callaway, Perri, Zagórska, Anna, Rothlin, Carla V., Nimmerjahn, Axel, Lemke, Greg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358512/
https://ncbi.nlm.nih.gov/pubmed/27049947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17630
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