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Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities

The TAM receptor tyrosine kinases Tyro3, Axl, and Mer regulate key features of cellular physiology, yet the differential activities of the TAM ligands Gas6 and Protein S are poorly understood. We have used biochemical and genetic analyses to delineate the rules for TAM receptor–ligand engagement and...

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Autores principales: Lew, Erin D, Oh, Jennifer, Burrola, Patrick G, Lax, Irit, Zagórska, Anna, Través, Paqui G, Schlessinger, Joseph, Lemke, Greg
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206827/
https://ncbi.nlm.nih.gov/pubmed/25265470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03385
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