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Reactive Oxygen Species Evoked by Potassium Deprivation and Staurosporine Inactivate Akt and Induce the Expression of TXNIP in Cerebellar Granule Neurons

The reactive oxygen species (ROS) play a critical role in neuronal apoptosis; however, the mechanisms are not well understood. It has been shown that thioredoxin-interacting protein (TXNIP) overexpression renders cells more susceptible to oxidative stress and promotes apoptosis and that the activati...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Zaragoza-Campillo, Marco Antonio, Morán, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358461/
https://ncbi.nlm.nih.gov/pubmed/28367274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/8930406
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