Potassium Deprivation-Induced Apoptosis of Cerebellar Granule Neurons: A Sequential Requirement for New mRNA and Protein Synthesis, ICE-Like Protease Activity, and Reactive Oxygen Species

Potassium (K(+)) deprivation-induced apoptosis of cerebellar granule neurons requires new mRNA and protein synthesis. Using a fluorogenic substrate for interleukin-1β converting enzyme (ICE), we show that K(+) deprivation of cerebellar granule neurons induces cycloheximide-sensitive ICE-like proteas...

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Publicado en:J Neurosci
Autores principales: Schulz, Jörg B., Weller, Michael, Klockgether, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1996
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579033/
https://ncbi.nlm.nih.gov/pubmed/8764657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-15-04696.1996
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